UPCOMING TESTING

PFAS Testing

Safeguard community health and product safety with fast, accurate, and reliable PFAS analysis

OVERVIEW

What Are PFAS Compounds?

PFAS, or per- and polyfluoroalkyl substances, are a large family of thousands of synthetic (man-made) chemicals that have been widely used since the 1940s to make products resist heat, water, grease, and stains.

At a molecular level, they rely on an incredibly strong carbon-fluorine bond that nature cannot break down, meaning these chemicals build up permanently in the environment and our bodies.

Today, PFAS compounds are a major global focus for regulators and health officials alike, as widespread exposure to these persistent chemicals is linked to serious health risks and business.
Laboratory beakers used in chemical analysis
PFAS ANALYSIS METHODS

What is PFAS Testing?

PFAS testing requires highly specialized laboratory techniques because these compounds are often present at trace concentrations, and contamination can occur easily during sampling, preparation, or analysis.
PPB Analytical provides high-sensitivity PFAS analysis using EPA Method 1633 and advanced Liquid Chromatography–Tandem Mass Spectrometry (LC-MS/MS) instrumentation. Our PFAS testing services support environmental monitoring, site assessment, regulatory compliance, remediation programs, product development, and quality assurance.

EPA Method 1633 represents a major advancement in standardized PFAS analysis. Earlier EPA PFAS methods focused primarily on drinking water, creating a need for a validated method that could be used for more complex environmental samples.

The U.S. Environmental Protection Agency developed Method 1633 in collaboration with the U.S. Department of Defense to address this analytical gap. The method was developed through multiple draft revisions and an extensive multi-laboratory validation process, establishing a consistent approach to PFAS analysis across aqueous, solid, and tissue matrices.

KEY INSTRUMENTS

Lab Equipment for PFAS Testing

Automated Solid-Phase Extraction (SPE)

Automated SPE systems prepare and concentrate PFAS from water and other sample matrices before analysis. They improve extraction consistency, reduce manual handling, and help achieve the low detection limits required for trace-level PFAS testing.

LC-MS/MS for PFAS Testing

LC–MS/MS Analysis

Liquid chromatography–tandem mass spectrometry is the primary technique used for targeted PFAS identification and quantification. It separates individual PFAS compounds and measures them at very low concentrations with high sensitivity and selectivity.

WHY IT MATTERS

The Biological Reality vs. The Business Necessity

Long-term exposure to trace PFAS is linked to severe systemic health issues:

  • Increased cholesterol levels
  • Thyroid disorders
  • Reduced immune system response
  • Liver and kidney damage
  • Developmental effects in children
  • Increased risk of certain cancers

Leaving operations untested is an operational and legal liability:

  • Meeting evolving regulatory standards
  • Protecting municipal drinking water
  • Monitoring remediation projects
  • Proving product & packaging safety
  • Mitigating legal & financial risks
  • Securing defensible environmental data
TESTING SCOPE

PFAS Contamination Matrix

EPA Method 1633 can be applied to a broad range of matrices, making it suitable for diverse regulatory and investigative needs.

Wastewater

Groundwater

Person holding a handful of dark soil and earth over a grassy field

Soil and Sediment

Small green plant sprout growing out of dark, nutrient-rich biosolids soil

Biosolids

Food Products

Consumer Goods

The method incorporates isotope-dilution quantitation, matrix-specific sample preparation, and comprehensive quality-control procedures. These controls are particularly important for PFAS analysis because background contamination, matrix interference, and analyte losses during sample handling can significantly affect trace-level results. 

By offering EPA Method 1633, PPB Analytical provides clients with a standardized and defensible analytical approach for environmental investigations, discharge monitoring, remediation projects, and evolving regulatory requirements. Our PFAS testing services are being developed to meet the growing demand for high-quality environmental and product testing.

ANALYTES DETECTED

PFAS Compounds We Test for

Perfluoroalkyl carboxylic acids

PFBA

PFPeA

PFHxA

PFHpA

PFOA

PFNA

PFDA

PFUnA

PFDoA

PFTrDA

PFTeDA

Perfluoroalkyl sulfonic acids

PFBS

PFPeS

PFHxS

PFHpS

PFOS

PFNS

PFDS

PFDoS

Fluorotelomer sulfonic acids

4:2FTS

6:2FTS

8:2FTS

Perfluorooctane sulfonamides

PFOSA

NMeFOSA

NEtFOSA

Per- and polyfluoroether carboxylic acids

HFPO-DA

ADONA

PFMPA

PFMBA

NFDHA

Ether sulfonic acids

9Cl-PF3ONS

11Cl-PF3OUdS

PFEESA

Fluorotelomer carboxylic acids

3:3FTCA

5:3FTCA

7:3FTCA

EIS Compounds
13C4-PFBA
13C5-PFPeA
13C5-PFHxA
13C4-PFHpA
13C8-PFOA
13C9-PFNA
13C6-PFDA
13C7-PFUnA
13C2-PFDoA
13C2-PFTeDA
13C3-PFBS
13C3-PFHxS
13C8-PFOS
13C2-4:2FTS
13C2-6:2FTS
13C2-8:2FTS
13C8-PFOSA
D3-NMeFOSA
D5-NEtFOSA
D3-NMeFOSAA
D5-NEtFOSAA
D7-NMeFOSE
D9-NEtFOSE
13C3-HFPO-DA
NIS Compounds
13C3-PFBA
13C2-PFHxA
13C4-PFOA
13C5-PFNA
13C2-PFDA
18O2-PFHxS
13C4-PFOS

Ready to Protect Your Operations?

By investing in advanced instrumentation, validated analytical methods, and continuous staff training, PPB Analytical is expanding its capabilities to support municipalities, manufacturers, environmental consultants, researchers, and regulatory agencies with reliable PFAS analysis.